The following questions were sent in concerning telomeres, telomerase, TA-65 and the Life Length assay as offered in the U. S. by adltests.com. Question 1: Is the database mainly constructed in the US? Answer: The database is worldwide but the bulk of the database comes from the U.S. The only lab currently offering the Life …
Telomeres and longevity – questions from readers Read More »
At the end of 2010, one of my least favorite journals, JAMA, published a very important and surprisingly forward-thinking (for them) article on telomere length and cancer. The study was a large Meta-analysis of telomere length and the likelihood of getting cancer. People were divided into “quartiles” according to telomere length. Basically, this means there …
Short telomeres are associated with decreased cancer survival Read More »
Over the past couple of days, I have dug pretty deep into the metabolic associations between obesity, diabetes, and short telomeres. The end result is of course, accelerated aging. But, more and more I have to tell you, I think aging is the real cause, or at least a major contributing factor to many of …
Aging fat as a cause for diabetes – the role of short telomeres Read More »
Heart disease has one of the longest standing associations with short telomeres. Recently a similar association was established for strokes (thrombotic ((clot) and hemorrhagic (bleeding)). The limitations of these studies in terms of direct correlation are that they are not using modern technology to determine the shortest telomere lengths or percentage. They are still using …
A recent German study has found an association between familial and non familial malignant melanoma and the telomerase gene. I think we should talk about this because it shows where the seemingly unending association with telomerase and cancer came/comes from. First concept: Cancer cells are not normal. They are the result not only of loss …
The monster is not born immortal: When telomerase drives cancer Read More »
Warning: this blog is long, somewhat complicated, very controversial, likely to make me enemies, likely to be 100% true and an honest reflection of my personal experience and likely to alienate anyone with a different agenda! So be it. Try to focus long enough to read it all, because it will do your telomeres a …
Note the abbreviation “kb” means kilobases as in thousands of base pairs. So 3 kb = 3000 base pairs. At a conference I spoke at recently, I was asked why telomerase does not replicate the “full DNA duplex of telomeres”. I was not sure if they were asking why telomeres shorten, if there is an …
I am getting a bit sick of all the BS that people are sending me, saying whatever product they represent (usually by an MLM ) is superior to TA-65. I allow dissenting opinions, because no one is ever right 100% of the time, including me. Over the past few months I have publicly retracted statements …
I have never been accused of adopting the “Popular Opinion”. Moreover, I make it a point to try to disabuse people of false notions. The problem is of course touched upon in the blog below, “The Connectivity Trap”, because we have created a totally open forum for human interaction. We have also created a totally …