Today’s Super Holiday Sale Item Pro Life PB is on sale with free shipping TODAY!

You may be wondering the role the microbiome plays in your health.  The obvious role is in your gut health but the effects of the microbiome reach far and wide in your body.

Let’s start with absorption of all those Great Longevity Edge supplements you are taking!

The microbiome is responsible for maintaining the acid/alkaline content of the gut, the way things are absorbed and even metabolized (metabolism starts in the gut with the initial processing of what you take in happening BEFORE you absorb anything!).

Then there is its’ role in obesity.  The microbiome processes food and makes short chain fatty acids which then are taken in by the intestines and feed YOU. Specifically, you are at least 20% fed by bacterial metabolites that are affected by the specifics of what you take in! Certain foods including the artificial sweetener saccharin produce MORE fat even though they have zero calories.  In other words, you bacteria can make calories by processing foods you cannot! This is the reason why some people eating diet foods/sodas etc get fatter on their diets!

Another huge huge role is immunity.  The bacteria help with what is known as antigen processing to the gut immune system which is in direct contact with your over all immunity. Poor gut bacteria health, poor immune health or even possible an auto-immune disease.

I could go on and on with the science but hey, it’s the Holidays and you get the picture!  In this picture should be a super well-designed pro/pre-biotic like Pro Life Pb on sale with free shipping in CONUS so Act Right Now because it’s going fast and we pull the sale tonight!

Here’s to your (Gut) health!


Dr Dave

Ok so we are back in action with all the great stuff that we didn’t get to before the Holiday!

Today’s featured Item will help you “wash” down some of the Holiday excesses you may find are all too tempting.

Pro Life is the Probiotic that keeps on giving.  Packed with all the right cultures, enterically coated to get past the stomach without upsetting it, and with pre-biotics to feed those good gut Bacteria it stands alone in quality.

And you can get it now dirt cheap with fee shipping.

Rebalance that belly and feel better about the Holidays!


Dr Dave

OK if you want the benefits without the science click here.

If you want to learn a bit more here goes:

Humans did not consume nearly the amount of carbs and sugar they do now until around 10,000 years ago.

Three Big Things have led us down the path to where our Carb intake is causing problems with our health.

  • Agriculture featuring mostly grains (carbs)
  • The introduction of refined sugar in the west (carbs)
  • The excessive focus on cheap fast hitting carbs in the post WW2 era by Big Food.

There is no time in the year where refined simple carb consumption does more damage to you health than now in the Holiday Season.

Let’s face it we may all want to cheat a little…or a lot.

You can however cover yourself and support a healthy blood sugar with Sugar Balance Support Formula using Mother Nature to combat the ravages of Big Food.

It wouldn’t hurt to avoid cookies, cakes, pies, sugary drinks and of course alcohol.

But if that sounds like wishful thinking get some help with SBSF which is on Sale Right Now at super low super easy pricing!

Break the cycle!!!!



In case you missed it (judging by the emails we’ve been getting there are quite a few of you!) for the next few hours I’m going to put The Immortality Edge Packs & Energy X Maxx back on sale. Once it’s over, it’s over so take advantage now!

The microbiome-also known as the bacteria that live in your gut- is a big part of how things happen in your body.

While not directly related to aging YET, it is directly affected by age and is huge in terms of your overall health.

You’ve heard me say a thousand times, “Take Care of Your Telomeres”, well now, today I am going to tell you how to take care of your microbiome so you can reap the maximum benefits from these hopefully symbiotic bacteria, and not have to deal with an unhealthy microbiome.

But first a few facts you should know about the microbiome:

1) An unhealthy microbiome is an unhealth person! The microbiome can actually become pathologic and cause disease. The best studied one is anti-biotic induced colitis caused by C. Difficile and other species.

2) The microbiome is the reason “calories are not calories” and why some non-nutritive and non-caloric sweeteners can potential cause hunger and weight gain. The microbiome processes and ferments many of the things that we put into our bodies even those that are “non-digestible” and makes things from them that can be used for calories or to feed both good and bad bacteria in the gut.

3) Because of #2 the microbiome is critical for absorption and transport of certain vitamins and minerals.

OK now here are some tips on getting it healthy.

1) First identify whether or not you have big food type sensitivities. I am not talking about the so-called avoidance diets but BIG things like gluten and dairy (usual lactose). For most people these are sensitivities rather than true allergies. The tip is if you feel bad, get bloated, gassy and experience a change in bowel habits. These are usually not subtle, you know if you pay attention that what you ate got you feeling this way. Similarly, if you feel really really tired after you eat but you did not overeat, changes are your body is reacting negatively to a food group like dairy or gluten. Try eliminating one of them at a time.

2) Maintain some vegetable mater in your diet including cruciferous vegetables like broccoli and cauliflower. For me I have to buy them and keep them visible in the fridge because my high fat diet is otherwise very filling and I don’t feel like eating more. So, I eat them first. This is a great way to do calorie restriction and intermittent fasting routines as well because the non-digestible fiber fills you.

3) This may sound strange but don’t get too dehydrated. Hydration status affects the gut in a big way so don’t neglect water consumption especially if you are in a warm climate or working out hard.

4) If your diet is suspect or you are dealing with a less than optimal microbiome don’t forget to supplement with a multi-vite!!!!  Consider it an insurance policy to keep your entire body in optimum support.

5) Consider fermented foods. Things like Sauerkraut and Kimchee or Kefir are great sources of healthy bacteria. The problem with the later is they always always always add sugar in store bought so see if there are any raw dairy farms around, or get some Kefir grains by mail! Its hard to make your own Kefir unless you have the true non pasteurized culture in what you buy and some good raw milk but you might want to try it. It can be an eye opener! At least 50% of the time you wind up with spoiled milk and no Kefir. If you use raw derived Kefir and raw milk you get something you can propagate for weeks that never spoils. By the way the milk microbiome is the reason raw milk keeps in your fridge 2-3 times longer than store bought. Store bought has no defense against bad bacteria and goes rotten in 5-7 days even when kept cold. Once you open it you start the process!

6) Take a Probiotic.  Mine is enteric coated to make it past the stomach and contains pre-biotics to foster healthy growth of the cultures.

7) Avoid alcohol tobacco and cannabis products! It’s a shame I have to say it but if your gut is healing don’t beat it up!!! You need 6 weeks of abstinence before you indulge if you do those kinds of things.
If you don’t do any of the things 1-6 above then you really really really need my probiotic!!!! <<<Link>>>

Personally, I follow my own guidelines 90+% of the time but I still take Pro Life PB daily.

Take Care Of Your Gut!!!!


How do you combat the Pied Piper of Aging?

Showing Up and having good habits Really Is Half the Battle!
Now I will expand on this a bit but first I want to share with you  a few quotes I really enjoy.

Among them is the anonymous, “Do nothing You’ll be just as productive!” and “Everything is a Science Project”.

I think that applies to certain situations nicely but not to the ones we actually exert control over. In our age of more decisions/choices than time available to sensibly make them or situations where other people create the infrastructure that we have to comply with those quotes work.

But in your life, and my life, where there ARE things that are very important and worth trying to exert our influence on, I have a better quote- this one from Aristotle.

We are the sum total of our habits!

If we take that on faith from one of our wisest elders you can see how showing up becomes a hugely important aspect of achievement and satisfaction… and health.

I used to own a different company that bore my name. And I had small stickers made up with my smiling face on it asking, “Did you take your Fish Oil today?”

It’s a great question and while it may not apply to everything I make, things like Fish Oil and Young Life Daily  are dishes best served daily, especially in today’s surrounding toxic environment and poor soil quality.

So, Did You?!

Aging is actually a kind of habit your body gets used to. Something is missing, overdone, or damaging and your body makes a short-term decision to use resources to fix it. Staying alive and reasonably healthy for the next minute is more important than staying alive and healthy for the next year or decade.

Some things get fixed, others don’t and in what scientists have called “antagonistic pleiotropy” * some decisions have negative long-term consequences with short term gain.

Much of the negative is due to molecules absent from our diets and our nutrition. Along with fish oil, the Young Life Daily you covers the common and not so common things missing that your body is probably craving for if: you are over 38, you don’t sleep enough, you work out hard, or you are under a lot of stress.

You may have to pay the pied piper of aging, but maybe you don’t have to pay as high a price as you think.

So, Did You?!


*Antagonistic pleiotropy has been championed by some heavy hitting scientists but no me. There is no gene for aging ever found in scientific study, nor is there any real youth gene other than perhaps telomerase. Clever scientists have recently adapted this theory to now include epigenetics which threw a monkey wrench into many a scientist’s career. Aging is epigenetic and, in most cases, falls within the “you can control” it maybe even eventually reverse it. Buy yourself some runway!

Sadly, we just got a notice that several of our Raw Material costs are going to go up significantly in the extreme near future.

If you want to lock into the current pricing you can do so by ordering on subscription/continuity now as I have made a promise to all my friends and customers out there that once they are on, the price stays the same as long as they are on no matter what the raw costs increase too.

At least Two products are currently affected BIG TIME and one moderately so for the moment.

Sweet Sleep Z is going to undergo a significant price increase because of the Theanine supply.

Apparently, someone has invented a drug based on this raw material and the company would rather sell to the Pharmaceutical Industry than us. Go Figure!!!

So, if you need an all-natural sleep aid that is non-habit forming and contains no drugs this is it and now is the time to get it.

Next is Sugar Balance Formula. You may already know my penchant for the ketogenic diet and the many blogs I have written for years now about my experiences with it.

I have also said that I don’t care what diet you are on- I am done preaching diet to people because its like religion to too many- just reduce your calories and manage your insulin secretion. This is especially true if you are on hormonal therapy.

Simply put insulin/sugar management is one of the most critical things you can do to prevent pre-mature aging and death. And we are doing such a good job of it we are now in the middle of an incipient diabetes epidemic where people are taking drugs for “pre-diabetes” or to prevent pre and post diabetes.

If this sounds nonsensical to you it is. I don’t know what is driving up people’s blood sugars (other than the massive amounts of carbs in our diets) but I think there are toxins and environmental exposures that make watching, controlling and reducing insulin secretion and sugar in the diet a 100% absolute must

Right Now.

Big Pharma agrees with me and has begun producing their new darling (which is a very old old darling) metformin and hinting that it might even help prevent cancer. Can you imagine what would happen to me if I so much as vaguely mentioned the words “supplements” and “cancer” in the same sentence!

Anyway, Goat’s Rue is one of the raws in Sugar Balance  and as demand goes so does price so that product is going to incur a price increase any day now!

If you believe like I do- that sugar is a major cause of illness and aging, and you need some support with yours, get on subscription now and take advantage of locking into the current pricing while it’s still available.

Sleep and sugar management are 2 of the most potent anti-aging tools in my book!


Dr Dave

PS remember we have hugely discounted case prices on all of our products including these.  Case prices will also go up to reflect the increase in raw materials very soon. So consider your needs for the rest of the year!

Over the past several weeks I have attempted to decipher some of the research behind probiotics and several things that may affect the health of your gut’s bacteria known as the microbiome.

As a reminder this is still, contrary to what some people would have you believe, a new field with much to discover especially in real live people. Much of what we know comes from animal models and we know far more about the mouse microbiome than we do the human one.

This has not stopped people from making broad sweeping generalizations and exceeding the data sets by far in an effort to be what I call “the firstest with the mostest”.

This seems to be a prerequisite in the field of supplement marketing and leads to all kinds of wild but generally harmless (and often worthless) creations that allow companies to say they were first with a new radical discovery. There is also a disturbing trend among anti-aging and regenerative medicine followers to try seriously unproven approaches suggested by non-medical personal.

Today we need to take a quick look at how the gut bugs may be affected by diet choices.

A recent comparison between the Mediterranean Diet and a “typical Western diet” is instructive.
The pre-clinical study was designed as follows and is described in the quote below from Wake Forrest Medical Center:
“The Western diet consisted of lard, beef tallow, butter, eggs, cholesterol, high-fructose corn syrup and sucrose, while the Mediterranean diet consisted of fish oil, olive oil, fish meal, butter, eggs, black and garbanzo bean flour, wheat flour, vegetable juice, fruit puree and sucrose. The diets had the same number of calories.”

The outcomes suggested a 7% increase in “good bacteria” versus only a 0.5% increase by the typical Western Diet.

The inclusion of what sounds like a ton of sugar and HFCS is probably the tipping point, but notice the “bad” diet still had a small increase in “good” bacteria.

I mention this because the tendency of internet headlines is to use verbiage that implies that something “bad” happened which is a far cry from the reality of the above. A similar situation occurred in the JAMA article on fish oil published last month. Headlines stated “Throw Out Your Fish Oil” completely ignoring ridiculous study design and even the 7% improvement in the rate of heart disease compared to similar studies on statins that showed a slightly higher 12% and required other medications to achieve that as well.

I believe a good Probiotic to be the fastest most reliable way to improve the quantity and quantity of your gut bacteria.

A good diet can make it even better! I am not sure we have a clear understanding of what that is just yet.*



*No, no one has compared it to a Vegetarian, Paleo, or Keto diet but if I had to guess I would say the same thing I always do: reduce your total calories by 30% and avoid sugar and excess carbs to manage your insulin. I do not advocate metformin for this unless you are already diabetic or pre-diabetic.
Instead you might try this!

It’s no surprise that a high-powered high monied marketing campaign has led to the resurgence of “leaky gut” as the cause of everything that ails you.

The original concept was helped along by the Paleo movement and by Paleo guru Dr Loren Cordain who is legendary in that community. Dr Cordain kindly took some time out of his busy schedule a few years back to talk to me. It was very enlightening and through him I met Dr. Stefan Lindberg another visionary.

The earlier work of Dr Cordain (once an exercise physiologist) focused on the immune system effects of certain dietary molecules found in grains and other standard food pyramid items. The concepts of anti-nutrients and auto immune diseases are among his contributions. Lately I see the good doctor’s name towards the end of most of the published studies suggesting that he is in a more supervisory role than a primary investigation role. Much of the work that comes out with his name on it now seems to beat up on the other non-Paleo food- milk and milk proteins.

I mention all this in the context of leaky gut because the more you read the more you see 3 things-

  1. There is a big difference between disease and health but often one is generalized to include the other. Examples of this include methylation patterns in diseases being applied to health and the behavior of things like the immune system and dietary molecules in people with Type 2 diabetes of inflammatory bowel diseases being generalized to heathy people.
  2. We really do not have a good definition of normal for many different things. As a corollary anyone interpreting results and trying to generalize them to non studied conditions should be really careful. I consider “healthy” a largely unstudied condition.
  3. Tracking the specific effects of individual nutrients is hard to do accurately and often yields disappointing results and more speculation.

Ok now you have the background of today’s point.

I think the laying of diseases and cures at the feet of “leaky gut” is far to premature to recommend the creation of an entire system of diets, nutrients and supplements. It has long been suggested that as we age our gut leaks because of “chronic low grade inflammation”. There is a well funded marketing machine out there that disagrees with me.

Personally, I have no doubt that the second thing is real- chronic low grade inflammation of the aged.

I am pretty sure I was the first to suggest that senescent cells created by telomere attrition were at least an important source of this progressive problem related to age, via the mechanism of the “senescent activated phenotype” or as DR Mike West calls it- Senstatic Activation. This coupled with other epigenetic events (not just methylation related!!!) probably results in the inflammatory phenotype and its resulted disease and repair-ability burdens we see in many people as they pass through middle age and beyond.

But I am less convinced that this inflammation automatically afflicts our gut as we age unless again UNLESS we have diseases like diabetes type 2 or inflammatory bowel disease which are by definition inflammatory (excess insulin in the early stages of Type 2 is not only unhealthy, it is inflammatory, globally in the body, and specifically at the source of insulin- the Beta islet cells).

This by the way, is the reason I now make a Sugar Balancing Formula. It is to give people a non drug (e.g. non metformin) alternative to the sugar problem that may await you if you ignore it.*

Its also worth mentioning that I cannot think of anything more anti-inflammatory than high potency fish oil especially when you are dealing with the whole body.

But there is one other thing I want to mention and that is the effect of probiotics.

While like so many things I have already mentioned the role of probiotics in the gut health is not fully expanded. But we know for sure that there is a healthy role for bacteria in the gut and we have some idea of what that requires: a pre-biotic, a probiotic and proper protections for both from stomach acid.

This is the main reason I waited so long to throw my hat in the probiotic ring. So much of what has come before was essentially worthless and I knew it.

Not so now!

Finally let me say that though I may change my mind if different or better evidence comes along, the hoopla and resurgence of leaky gut is just that-hype. At this moment I think it is a symptom of other inflammatory conditions that are best treated as I mentioned above not a cause of them (with the possible exception of inflammatory bowel disorders).



Here is a good review that is free to the public:
The gut microbiota and host health: a new clinical frontier

*Please note metformin is a drug that has use in diabetes. I am not suggesting you stop it or use my supplements in favor of it if you have that condition! Failure to specifically tell you this even if it seems obvious may constitute “failure to adequately disclose” information in the eyes of our dear friends at the alphabet agencies. Also note this a very open definition and as far as I know has not clearly defined legally anywhere. In similar fashion I suppose I should tell you that the products above are manufactured by me, otherwise you might not conclude what is obvious, and a “significant minority” of people (again not clearly defined what that means) might not make the painfully obvious conclusion and thus be deceived. If you think this is ridiculous so do I but yes, this is what it is coming to!!!

Leaky gut is anatomically defined as unhealthy gaps in the absorptive surface of the intestine. Supposedly the major cause is lectins and “anti-nutrients”- things that inflame the gut and interfere with nutrient absorption.

If you want a little science here it is: the gut has immune cells sitting on its surface as well that are supposed to guard you from nasty things in the food- things that might make you sick. These cells are also supposed to “educate” your immune system on a continuous basis so it can deal with toxins, bacteria and other inflammatory agents that you might ingest.

Along the way a balance is struck between these cells. If that balance in perturbed then your gut and your entire system may be perturbed. You may un balance your immune system. So far, the evidence is sketchy but there is some reasonable thought processes that suggest that some people with auto immune diseases have this as a contributing factor.

Remember Leaky Gut is a “syndrome” which means there is no clearly definable way to diagnose it.

As a result, its has been a catch all for many different problems and some people claim miraculous results and entire body habitus changes (weight loss, muscle building) and personality changes (happier, more productive better sleep) as well as overall decrease of resolution of joint pains and the ubiquitous “brain fog” (try spending less time on Facebook and your cell phone browsing nonsense!)

So, we are left with a situation that often permeates (no pun intended) the world of alternative medicine which I often inhabit.

What to do!?

Personally, I think I would start with a good probiotic and an honest assessment of my life choices and whether they have brought me happiness. I would look at sleep patterns and lifestyle choices like diet and exercise and try to improve those areas as needed.

There is no question that some illness like the latest epidemic of liver disease based on non-alcoholic fatty liver can cause changes in the intestine that might qualify as leaky gut. Similarly, the expansive use of non-nutritive sweeteners, specifically saccharin and the sugar alcohols can change the microbiome (bugs in your gut).

This is why probiotics may be the answer or at least part of it. It makes total sense to do what is needed to have a healthy bunch of little buddies in the gut to help you out.

But remember the inflammatory responses of your body are not limited to your gut-they are mostly global in your body, e.g. everywhere!

I maintain and always have that the single most important thing you can do for inflammation is get your Omega 3 doses  up to a reasonable level.

The gut is part of the equation though and a Probiotic works wonderfully there.

So, if you think you might have leaky gut, start by fixing your microbiome!


I have to admit I enjoy exercise a lot. I’ve enjoyed many different kinds of exercise and been exposed and even trained with some of the absolute visionaries of human performance. Even when I am traveling I can always find time for a good workout.

But exercise is not really as much of a transformation tool as the exercise industry would have you believe. Now before you start leveling criticism at me for this grand departure from the accepted dogma let me remind you I do have a CPT certificate and continue my education in the industry even though I don’t make a living that way.

I have written many blogs on the best kind of exercise  as well as diet which seem to be two inseparable topics for most people.

But for the moment I want you to separate them and digest these statements.

I view exercise as a fitness tool.  I diet as a weight loss tool.

If you ask me what would help the most people in the U.S. I would have to say diet at least at first.

While almost everyone who is overweight is also out of shape and it may seem artificial to separate the 2 ways of improving our bodies the truth is that each contributes to health in a very different fashion.

An average of 30 pounds weight loss for the typical overweight/obese American would go a lot farther than 3 hours a week in the gym in the first 12 to 18 months. Put another way, if I found a Genie in a bottle that would grant me one wish for the population of this country first, it would be weight loss.

Weight loss, especially significant weight loss revamps your body’s metabolism, resets your hormones, your sleep, your sex life and so on.  Exercise may do a lot of those things as well but it takes a lot longer.

Now with the American obsession with looking good..

I would be remiss if I didn’t tell you the 6 pack ab look is all about body fat, which in turn is linked to body weight. Again put another way, you will only see your 6 pack if you lose enough weight and fat to let it show, no matter how much exercise you do.

Now the corollary question of all this is can you be fat and fit?  That would depend on what you call fit. If you are looking for pure strength then you will find a lot of fat looking people who are very strong.  But they do not age well. Indeed the older we get the more being lean becomes super important.

And what about this common question: Can you do both together.  Again it depends.  If you are morbidly obese or seriously overweight I would stick with weight loss as the main focus and add in exercise slowly in increasing doses.

If you are already lean and strong and have endurance chances are you stopped reading this a long time ago.

You might, if you are a regular reader, even wonder why I am writing this. After all The Longevity Edge audience are probably among the fittest people in the world.

Two things: First we are getting a lot of notoriety out there in the big world and that means a lot of first timers are visiting looking for how to get started in an effective anti-aging program. Second I do a lot of traveling. I cannot help but notice how many of my fellow Americans are just plain fat.  I call it carb poisoning these days.  The bloated faces, waddling walks, giant bellies, etc there is far more of that amongst us than there are lean healthy specimens!

Worse TV has been taken over by reality shows! Part of that reality is preponderance of fat people. And that my friend is a real reality no matter how silly/phony the shows are!

If you want it all…

Is a 6 pack, leanness, power and strength then the ketogenic/Paleo diet has been a mainstay for me for a long time with great results.

I had someone ask me if I still look like I did when we introduced Energy X Maxx.  The truth is I am lighter and not quite as buff, but I am still OK with how everything looks and more than OK with how it feels to grow younger each year.

Stay tuned for a pic or two but remember this: I am anything but special and anything but an exception. I follow the same guidelines I give you and I do so with consistency including my supplementation, diet and exercise.

Trust me if it works for a genetically very average guy like me, YOU should have glorious results.

Here’s to you.